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Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Notify the Multiple Myeloma Research Foundation you are interested in this trial
NCT04771572
Age 13 +
Sex Both
Phase Phase 1
Third Opinion Trial Synopsis
In this clinical study, researchers are exploring a new treatment approach for patients with a specific type of blood cancer. The study focuses on using a combination of therapies to improve patient outcomes. Here are some key points about the study:
  • The treatment involves a unique combination of drugs that target the cancer cells in different ways, potentially leading to better results than traditional therapies.
  • Patients will receive the treatment in a controlled environment, allowing researchers to closely monitor its effects and adjust as needed.
  • This study is designed to evaluate not only the effectiveness of the treatment but also its safety and how well patients tolerate it.
  • Participants will be closely followed for a significant period, providing valuable data on long-term outcomes and any side effects.
  • The study aims to include a diverse group of patients to ensure the findings are applicable to a wide range of individuals affected by this condition.
Overall, this study represents an innovative approach to treatment, with the potential to improve the quality of life for patients and possibly lead to new standards of care in the future.
Third Opinion AI Generated Synopsis

Trial Summary
This is a Phase 1, multi-center, open-label study with a dose-escalation phase (Phase 1a) and a cohort expansion phase (Phase 1b), to evaluate the safety, tolerability, and PK profile of LP-118 under a once daily oral dosing schedule in up to 100 subjects.
from ClinicalTrials.gov

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