Third Opinion Trial Synopsis
Doctors are doing a study to see if two medicines, iberdomide and dexamethasone, can help people with a type of cancer called smoldering multiple myeloma. Iberdomide can help your body fight cancer, and dexamethasone is a medicine that can also help treat cancer. The doctors hope that giving these two medicines together can help stop the cancer from getting worse and make people feel better.

Trial Summary
This phase II trial studies the effects of iberdomide when given alone or in combination with dexamethasone in treating intermediate or high-risk smoldering multiple myeloma patients. Immunotherapy with iberdomide may induce changes in body's immune system and may interfere with the ability of cancer cells to grow and spread. Dexamethasone is a synthetic steroid (similar to steroid hormones produced naturally in the adrenal gland), and is used with other drugs in the treatment of some types of cancer. Giving iberdomide with dexamethasone my improve time to progression to symptomatic myeloma with improved tolerability.