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Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Notify the Multiple Myeloma Research Foundation you are interested in this trial
NCT05153330
Age 18 +
Sex Both
Phase Phase 1
Third Opinion Trial Synopsis
In this clinical study, researchers are exploring a new treatment approach for patients with a specific type of blood cancer. The study focuses on using a combination of therapies to improve patient outcomes. Here are some key points about the study:
  • The treatment involves a combination of different medications that target the cancer cells in unique ways.
  • It aims to enhance the effectiveness of existing therapies by using a multi-drug approach.
  • Patients will receive close monitoring throughout the study to assess how well the treatment is working and to manage any side effects.
  • This study is unique because it combines therapies that have not been used together before, potentially leading to better results.
  • Participants will have the opportunity to contribute to research that could improve future treatments for others with the same condition.
Overall, this study represents an innovative approach to treating blood cancer, with the hope of providing more effective options for patients.
Third Opinion AI Generated Synopsis

Trial Summary
A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with KMT2A/ MLL1r, NPM1 mutations), DLBCL, MM, and CLL/SLL.
from ClinicalTrials.gov

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