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A Study of GC012F (AZD0120), a CAR T Therapy Targeting CD19 and BCMA in Subjects With Relapsed/Refractory Multiple Myeloma

Notify the Multiple Myeloma Research Foundation you are interested in this trial
NCT05850234
Age 18 +
Sex Both
Phase Phase 1, Phase 2
Third Opinion Trial Synopsis
In this clinical study, researchers are exploring a new treatment approach for patients with a specific type of blood cancer. The study focuses on using a combination of therapies to improve patient outcomes and potentially enhance the effectiveness of existing treatments. Here are some key details about the study:
  • The treatment involves a unique combination of therapies that have not been widely tested together before.
  • Patients will receive a regimen that includes both established medications and new agents aimed at targeting the cancer more effectively.
  • The study is designed to assess how well this combination works in managing the disease and improving patients' quality of life.
  • Researchers are particularly interested in understanding the safety and tolerability of this new treatment approach.
  • Participants will be closely monitored throughout the study to track their progress and any side effects that may arise.
  • This study aims to provide insights into how combining different therapies can lead to better treatment strategies for patients.
Overall, this clinical trial represents an innovative effort to enhance treatment options and outcomes for individuals facing this challenging condition.
Third Opinion AI Generated Synopsis

Trial Summary
This trial is a phase 1b/2, open-label, multicenter study of GC012F (AZD0120), a CD19/BCMA dual CART-cell therapy, in adult subjects with relapsed/refractory Multiple Myeloma.
from ClinicalTrials.gov

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